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Ombrabulin hydrochloride

CAS No. 253426-24-3

Ombrabulin hydrochloride ( AVE-8062;AVE-8062A;AC-7700 )

产品货号. M13754 CAS No. 253426-24-3

A novel combretastatin A-4 derivative that strongly stanches tumour blood flow and inhibits growth of tumours developing in various tissues and organ.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
10MG ¥5292 有现货
50MG ¥15876 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Ombrabulin hydrochloride
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    A novel combretastatin A-4 derivative that strongly stanches tumour blood flow and inhibits growth of tumours developing in various tissues and organ.
  • 产品描述
    A novel combretastatin A-4 derivative that strongly stanches tumour blood flow and inhibits growth of tumours developing in various tissues and organ; a vascular-disrupting agent.Ovarian Cancer Phase 2 Clinical
  • 同义词
    AVE-8062;AVE-8062A;AC-7700
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Other Targets
  • 研究领域
    Cancer
  • 适应症
    Ovarian Cancer

化学信息

  • CAS Number
    253426-24-3
  • 分子量
    438.90
  • 分子式
    C21H27ClN2O6
  • 纯度
    >98% (HPLC)
  • 溶解度
    10 mM in DMSO; Methanol: ≥ 30 mg/mL
  • SMILES
    O=C(NC1=CC(/C=C\C2=CC(OC)=C(OC)C(OC)=C2)=CC=C1OC)[C@@H](N)CO.[H]Cl
  • 化学全称
    Propanamide, 2-amino-3-hydroxy-N-[2-methoxy-5-[(1Z)-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl]-, hydrochloride (1:1), (2S)-

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Hori K, et al. Br J Cancer. 2002 May 20;86(10):1604-14.
2. Kim TJ, et al. Cancer Res. 2007 Oct 1;67(19):9337-45.
3. Sessa C, et al. Clin Cancer Res. 2013 Sep 1;19(17):4832-42.
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